I am a Research Associate (postdoc) in the Brenton and Markowetz labs at Cancer Research UK Cambridge Institute, University of Cambridge and a Honorary Fellow in the Department of Computing and Information Systems at The University of Melbourne.
As a computational biologist I work on methods to identify genomic copy-number changes associated with treatment resistance in high-grade serous ovarian cancer (HGSOC). We use whole-genome sequencing of longitudinally collected HGSOC samples to achieve this. In addition, I work on methods that model tumour heterogeneity and subclonal tumour evolution using structural variants as part of the Pan Cancer Analysis of Whole Genomes project.
Previously, I was overseeing the computational biology component of a number of projects in urological cancer research in collaboration with A/Prof Chris Hovens and Dr Niall Corcoran at the Australian Prostate Cancer Research Centre @ Epworth and Royal Melbourne Hospital.
Over the past few years I have been involved in various initiatives as part of the International Society for Computational Biology, and I am currently part of the organising committee for the junior principal investigators in computational biology.